Name: Butyl acrylate
CAS Number: 141-32-2
UN Number: 2348
Formulae: C7H12O2
Name: Butyl acrylate
CAS Number: 141-32-2
UN Number: 2348
Formulae: C7H12O2
Physicochemical properties/Characteristics
-
FED
Physical behaviour (GESAMP, 2016)
1, 2 -
128.171
Molecular Weight
2
(g/mol) -
0.89
Density
2
(kg/L) -
0.73
Vapour pressure
2
(KPa; 25ºC) -
2000
Water solubility
2
(mg/L; 23ºC) -
0.79
Dynamic viscosity
2, 3
(mPa.s; 25ºC) -
-64.6
Melting point (ºC)
2 -
145.0
Boiling point (ºC)
2 -
5.1
Volatilization half-life (days)
4
- G: gas; D: dissolver; E: evaporator; F: floater; S: sinker; GD: gas/dissolver; DE: dissolver/evaporator; FD: floater/dissolver; FE: floater/evaporator; FED: floater/evaporator/dissolver; Fp: persistent floater; SD: sinker/dissolver
- Values collected from the literature and public databases e.g. PubChem
- “-“ corresponds to values not found
- Values estimated with models of the EPI suiteTM
Fugacity/Persistence
-
3.05
Air
4, 5 -
96.60
Water
4, 5 -
0.02
Soil
4, 5 -
0.29
Sediment
4, 5 -
7.3
Persistence (days)
4
- Values estimated with models of the EPI suiteTM
- In the present study, only emissions in water were considered
Physicochemical degradation/Biodegradation
-
9.3
Atmosferic Oxidation (hours)
4 -
R
Biodegradation rate (GESAMP, 2016)
6, 7 -
0.93
Aerobic biodegradation probability
4 -
4.16 days
Primary aerobic biodegradation half-life
4, 8 -
3.35 days-weeks
Ultimate aerobic biodegradation half-life
4, 8 -
-
Hydrocarbon Biodegradation half-life (days)
3, 4 -
0.47
Anaerobic Biodegradation probability
4
- “-“ corresponds to values not found
- Values estimated with models of the EPI suiteTM
- Results obtained from the literature
- GESAMP criteria consider substances to be “readily biodegradable” (R) if, in 28-day biodegradation studies, the following levels of degradation are achieved: in tests based upon dissolved organic carbon (DOC) die-away: ≥ 70%; or in tests based upon oxygen depletion or carbon dioxide generation: ≥ 60% of the theoretical maxima; or where only chemical oxygen demand (COD) and biochemical oxygen demand (BOD5) data are available, the ratio of BOD5/COD ≥ 0.5; or where other convincing scientific evidence is available to demonstrate that the substance can be degraded (biotically and/or abiotically) in the aquatic environment to a level of > 70% within a 28-day period. Otherwise they are “not readily biodegradable” (NR) (GESAMP, 2014).
- See Table 1 in the supplementary material for more information on the rating reported by Boethling et al. (1994)
Bioaccumulation/Biotransformation
-
0.06
Biotransformation half-life (days)
2 -
2.36
Partition coefficient (log Kow)
2 -
10.8
Bioconcentration factor (BFC)
4 -
2
Bioaccumulation rate (GESAMP, 2016)
9 -
1.86
Adsorption coefficient (log koc)
2
- Values collected from the literature and public databases e.g. PubChem
- Values estimated with models of the EPI suiteTM
- See Table 2 in the supplementary material for more information on Bioaccumulation rate classification (GESAMP, 2014)
Aquatic Toxicity
-
3
Acute toxicity (GESAMP, 2016)
10 -
-
Chronic toxicity (GESAMP, 2016)
3, 10
- “-“ corresponds to values not found
- See Table 3 in the supplementary material for more information on Aquatic Toxicity classification (GESAMP, 2014)
Acute Mammals/Human health effects
-
1
Oral Toxicity (GESAMP, 2016)
11 -
1
Dermal toxicity (GESAMP, 2016)
11 -
1
Inhalation toxicity (GESAMP, 2016)
11 -
2
Skin irritation & corrosion (GESAMP, 2016)
11 -
2
Eye irritation & corrosion (GESAMP, 2016)
11 -
0
Toxicity
12 -
0
Severity
12
- See Table 4 in the supplementary material for more information on Human health (Toxic effects to mammals) classification (GESAMP, 2014)
- For more information on Toxicity and Severity scores consult Harold et al. (2014)
Chronic Human/Mammals health effects
-
1
Carcinogenicity (IARC)
3, 13 -
No
Mutagenicity (GESAMP, 2016)
11 -
No
Reprotoxicity (GESAMP, 2016)
11 -
Yes
Sensitizing to skin (GESAMP, 2016)
11 -
Yes
Aspiration hazard (GESAMP, 2016)
11 -
No
Target Organ Toxicity (GESAMP, 2016)
11 -
No
Sensitizing to respiratory system (GESAMP, 2016)
11 -
No
Neurotoxicity (GESAMP, 2016)
11 -
No
Immunotoxicity (GESAMP, 2016)
11
- “-“ corresponds to values not found
- See Table 4 in the supplementary material for more information on Human health (Toxic effects to mammals) classification (GESAMP, 2014)
- See Table 5 in the supplementary material for more information on IARC classification
Toxicity tests results
PNECseawater:
0.21 µg/L
PNECwater, intermittent:
21 µg/L
Algae
-
EC50
Parameter
1 -
3.18
Concentration
(mg/L) -
Algae - Desmodesmus subspicatus
Species
-
Biomass
Endpoint
-
Freshwater; Static; 72h-exposure
Observations
1
-
EC50
Parameter
1 -
5.28
Concentration
(mg/L) -
Algae - Desmodesmus subspicatus
Species
-
Cell growth
Endpoint
-
Freshwater; Static; 72h-exposure
Observations
2
- Organization for Economic Cooperation and Development; Screening Information Data Set for n-Butyl acrylate, CAS #141-32-2 (October 2002) as cited in the Pubchem database. Available at: https://pubchem.ncbi.nlm.nih.gov/compound/butyl_acrylate#section=Ecotoxicity-Values (accessed November 14, 2015)
Invertebrates
-
EC50
Parameter
1 -
8.2
Concentration
(mg/L) -
Water flea - Daphnia magna
Species
-
Immobilization
Endpoint
-
Freshwater; Flow through; 48h-exposure
Observations
3
-
LC50
Parameter
2 -
230
Concentration
(mg/L) -
Water flea - Daphnia magna
Species
-
Intoxication; immobilization
Endpoint
-
Freshwater; Static; 20-22 °C; 24h-exposure; ≤ 24h age
Observations
4
- BASF; Safety datasheet Butyl acrylate (2005). Available at: http://www2.basf.us/acrylicmonomers/pdfs/Butyl_Acrylate_msds.pdf (accessed February 22, 2017)
- Bringmann G, Kuhn R; TR-79-1204, Literature Research Company, Annandale, VA: 26 p. as cited in the ECOTOX database. Available at: http://cfpub.epa.gov/ecotox/quick_query.htm (accessed November 14, 2015)
Fish
-
LC50
Parameter
1 -
22
Concentration
(mg/L) -
Ide - Leuciscus idus
Species
-
Mortality
Endpoint
-
Freshwater; Static; 19-20 °C; 72h-exposure
Observations
5
-
LC50
Parameter
1 -
5.2
Concentration
(mg/L) -
Rainbow trout - Oncorhynchus mykiss
Species
-
Mortality
Endpoint
-
Freshwater; Flow through; 96h-exposure
Observations
6
-
LC50
Parameter
1 -
2.1
Concentration
(mg/L) -
Sheepshead minnow - Cyprinodon variegatus
Species
-
Mortality
Endpoint
-
Saltwater; Flow through; 22.5-23.5 °C; 96h-exposure
Observations
7
Lowest
- Organization for Economic Cooperation and Development; Screening Information Data Set for n-Butyl acrylate, CAS #141-32-2 (October 2002) as cited in the Pubchem database. Available at: https://pubchem.ncbi.nlm.nih.gov/compound/butyl_acrylate#section=Ecotoxicity-Values (accessed November 14, 2015)
Mammals
-
LC50
Parameter
1 -
7.8
Concentration
(mg/L) -
Mouse
Species
-
Mortality
Endpoint
-
Acute; 2h-inhalation
Observations
8
-
LC50
Parameter
1 -
2730
Concentration
(ppm) -
Rat
Species
-
Mortality
Endpoint
-
Acute; 4h-inhalation
Observations
9
-
LC50
Parameter
2 -
10.3
Concentration
(mg/L) -
Rat
Species
-
Mortality
Endpoint
-
Acute; 4h-inhalation
Observations
10
-
LD50
Parameter
1 -
853
Concentration
(mg/kg) -
Mouse
Species
-
Mortality
Endpoint
-
Acute; intraperitoneal
Observations
11
-
LD50
Parameter
1 -
7561
Concentration
(mg/kg) -
Mouse
Species
-
Mortality
Endpoint
-
Acute; oral
Observations
12
-
LD50
Parameter
1 -
550
Concentration
(mg/kg) -
Rat
Species
-
Mortality
Endpoint
-
Acute; intraperitoneal
Observations
13
-
LD50
Parameter
1 -
900
Concentration
(mg/kg) -
Rat
Species
-
Mortality
Endpoint
-
Acute; oral
Observations
14
-
LD50
Parameter
1 -
2000
Concentration
(mg/kg) -
Rabbit
Species
-
Mortality
Endpoint
-
Acute; dermal
Observations
15
- Lewis RJ Sr; Sax's Dangerous Properties of Industrial Materials. 11th ed. Wiley-Interscience, Wiley & Sons, Inc., Hoboken, NJ. (2004)
- Organization for Economic Cooperation and Development; Screening Information Data Set for n-Butyl acrylate, CAS #141-32-2 (October 2002) as cited in the Pubchem database. Available at: https://pubchem.ncbi.nlm.nih.gov/compound/butyl_acrylate#section=Ecotoxicity-Values (accessed November 14, 2015)
References
Boethling RS, Howard PH, Meylan W, Stiteler W, Beauman J, Tirado N. 1994. Group contribution method for predicting probability and rate of aerobic biodegradation. Environ. Sci. Technol. 28: 459-465.
Bonn Agreement, 1994. European Classification System, Bonn Agreement: Counter-Pollution Manual. Bonn Agreement, London (Chapter 25).
GESAMP (IMO/FAO/UNESCO-IOC/WMO/WHO/IAEA/UN/UNEP Joint Group of Experts on the Scientific Aspects of Marine Environmental Protection), 2014. Revised GESAMP Hazard Evaluation Procedure for Chemical Substances Carried by Ships, 2nd edition. Rep. Stud. GESAMP No. 64, 126 pp.
GESAMP Composite List, 2016. ANNEX 5 – UPDATED GESAMP COMPOSITE LIST. Available at: https://edocs.imo.org/Final Documents/English/PPR 1-CIRC.3 (E).docx (Accessed: December 12, 2016).
Harold PD, Souza AS, Louchart P, Russell D, Brunt H, 2014. Development of a risk based prioritisation methodology to inform public health emergency planning and preparedness in case of accidental spill at sea of hazardous and noxious substances (HNS). Environ. Int. 72: 157-163.