PRINCIPLES OF ENVIRONMENTAL TOXICOLOGY AND CONTAMINATION (PART III)

Table of Contents

1. Index
2. UNIT 9 - Environmental risk assessment
3. UNIT 10 - Environmental risk communication
4. UNIT 11 - Modelling in Ecotoxicology
   1. Introduction
   2. Dynamic Energy Budget (DEB) models
   3. Toxicokinetic-Toxicodynamic (TKTD) models
   4. Coupling toxicity data to ecological models: effects at the population and ecosystem scales
5. UNIT 12 - Legislation
6. Glossary of key terms associated with environmental toxicology

Toxicokinetic-Toxicodynamic (TKTD) models

3.1. Introduction

An introduction to the toxicokinetic-toxicodynamic models (supplemented with different sources such as articles) is presented in chapter 6.

3.2. Case study

Read the following article:

doi:10.1371/journal.pone.0062472
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0062472

Answer the following questions:

1 - Explain the main aim of this experiment.

2 - Why was the toxicokinetic-toxicodynamic (TKTD) modelling used in this study?

3 - What were the main conclusions of this work?