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National R&D

CYANOMETAL

Discovery of cyanobacterial metal chelators: a multifunctional solution for Alzheimer´s disease

Principal Investigator
20230525_094752 - Mariana Reis
Researcher

Mariana Reis (PhD in Pharmacy – University of Lisbon, 2015) is a researcher at CIIMAR who is interested in the natural products chemistry of microalgae and cyanobacteria. These organisms produce a diverse array of organic chemicals that are just waiting for a novel biotechnological application. With her extensive experience in natural compounds isolation, structural elucidation, and molecular derivatization, she is involved in several projects whose goal is to provide microalgae and cyanobacteria-driven solutions to human health and environmental problems. She is also very engaged in scientific dissemination actions and training the next generation of scientists, through lectures and supervision of PhD, masters and undergraduate students.

RESEARCH GROUPS:

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The project CYANOMETAL aims to identify cyanobacterial metallophores as potential multifunctional metal chelators capable of modulating metal concentrations and inhibiting molecular Alzheimer’s Disease (AD) targets. By employing advanced genomics and metabolomics tools, the project links the production of metallophores by a rich biodiversity of cyanobacteria to the dysregulation of metal ions observed in AD, for new and effective treatments.

Leader Institution
CIIMAR-UP
Program
Programa Inovação e Transição Digital (COMPETE 2030), Portugal 2030 + Orçamento próprio (15%)
Funding
Other projects